@prefix fhir: <http://hl7.org/fhir/> .
@prefix loinc: <http://loinc.org/rdf#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<https://emahealth.io/fhir/pathology/Composition/EjemploPatologiaComposition> a fhir:Composition ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:Resource.id [ fhir:value "EjemploPatologiaComposition"] ;
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "https://emahealth.io/fhir/pathology/StructureDefinition/ema-pathology-composition" ;
       fhir:index 0 ;
       fhir:link <https://emahealth.io/fhir/pathology/StructureDefinition/ema-pathology-composition>
     ]
  ] ;
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ] ;
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: Composition EjemploPatologiaComposition</b></p><a name=\"EjemploPatologiaComposition\"> </a><a name=\"hcEjemploPatologiaComposition\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ema-pathology-composition.html\">EMA Pathology Composition</a></p></div><p><b>status</b>: Final</p><p><b>type</b>: <span title=\"Codes:{http://loinc.org 11526-1}\">Informe de estudio anatomopatológico</span></p><p><b>date</b>: 2026-04-10 12:00:00-0400</p><p><b>author</b>: <a href=\"Practitioner-EjemploPatologiaPractitioner.html\">Practitioner Paulina Herrera Donoso (official)</a></p><p><b>title</b>: Informe anatomopatológico — Biopsia de mama (AP-2026-000123)</p></div>"
  ] ;
  fhir:Composition.status [ fhir:value "final"] ;
  fhir:Composition.type [
     fhir:CodeableConcept.coding [
       fhir:index 0 ;
       a loinc:11526-1 ;
       fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
       fhir:Coding.code [ fhir:value "11526-1" ]
     ] ;
     fhir:CodeableConcept.text [ fhir:value "Informe de estudio anatomopatológico" ]
  ] ;
  fhir:Composition.subject [
     fhir:link <https://emahealth.io/fhir/pathology/Patient/EjemploPatologiaPatient> ;
     fhir:Reference.reference [ fhir:value "Patient/EjemploPatologiaPatient" ]
  ] ;
  fhir:Composition.date [ fhir:value "2026-04-10T12:00:00-04:00"^^xsd:dateTime] ;
  fhir:Composition.author [
     fhir:index 0 ;
     fhir:link <https://emahealth.io/fhir/pathology/Practitioner/EjemploPatologiaPractitioner> ;
     fhir:Reference.reference [ fhir:value "Practitioner/EjemploPatologiaPractitioner" ]
  ] ;
  fhir:Composition.title [ fhir:value "Informe anatomopatológico — Biopsia de mama (AP-2026-000123)"] ;
  fhir:Composition.section [
     fhir:index 0 ;
     fhir:Composition.section.title [ fhir:value "Datos clínicos" ] ;
     fhir:Composition.section.code [
       fhir:CodeableConcept.coding [
         fhir:index 0 ;
         a loinc:22636-5 ;
         fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
         fhir:Coding.code [ fhir:value "22636-5" ]
       ]
     ] ;
     fhir:Composition.section.text [
       fhir:Narrative.status [ fhir:value "generated" ] ;
       fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Mujer de 52 años. Nódulo palpable en mama derecha, cuadrante superior externo. Mamografía BI-RADS 4. Se solicita biopsia core.</div>"
     ]
  ], [
     fhir:index 1 ;
     fhir:Composition.section.title [ fhir:value "Descripción macroscópica" ] ;
     fhir:Composition.section.code [
       fhir:CodeableConcept.coding [
         fhir:index 0 ;
         a loinc:22634-0 ;
         fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
         fhir:Coding.code [ fhir:value "22634-0" ]
       ]
     ] ;
     fhir:Composition.section.text [
       fhir:Narrative.status [ fhir:value "generated" ] ;
       fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Se reciben 3 cilindros de tejido pardo-blanquecino, el mayor de 1.4 cm, incluidos en su totalidad en bloque A1.</div>"
     ]
  ], [
     fhir:index 2 ;
     fhir:Composition.section.title [ fhir:value "Descripción microscópica" ] ;
     fhir:Composition.section.code [
       fhir:CodeableConcept.coding [
         fhir:index 0 ;
         a loinc:22635-7 ;
         fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
         fhir:Coding.code [ fhir:value "22635-7" ]
       ]
     ] ;
     fhir:Composition.section.text [
       fhir:Narrative.status [ fhir:value "generated" ] ;
       fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Proliferación epitelial atípica formando nidos y trabéculas infiltrantes en estroma desmoplásico. Pleomorfismo moderado, índice mitótico intermedio. Compatible con carcinoma ductal infiltrante NOS, grado 2 de Nottingham (6/9).</div>"
     ] ;
     fhir:Composition.section.entry [
       fhir:index 0 ;
       fhir:link <https://emahealth.io/fhir/pathology/Observation/EjemploPatologiaSinopticoSeccion> ;
       fhir:Reference.reference [ fhir:value "Observation/EjemploPatologiaSinopticoSeccion" ]
     ], [
       fhir:index 1 ;
       fhir:link <https://emahealth.io/fhir/pathology/DocumentReference/EjemploPatologiaWSI> ;
       fhir:Reference.reference [ fhir:value "DocumentReference/EjemploPatologiaWSI" ]
     ]
  ], [
     fhir:index 3 ;
     fhir:Composition.section.title [ fhir:value "Diagnóstico" ] ;
     fhir:Composition.section.code [
       fhir:CodeableConcept.coding [
         fhir:index 0 ;
         a loinc:22637-3 ;
         fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
         fhir:Coding.code [ fhir:value "22637-3" ]
       ]
     ] ;
     fhir:Composition.section.text [
       fhir:Narrative.status [ fhir:value "generated" ] ;
       fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Carcinoma ductal infiltrante (NOS) de mama derecha, grado histológico 2 (Nottingham 6/9). ICD-O-3 8500/3.</div>"
     ] ;
     fhir:Composition.section.entry [
       fhir:index 0 ;
       fhir:link <https://emahealth.io/fhir/pathology/Observation/EjemploPatologiaDiagnostico> ;
       fhir:Reference.reference [ fhir:value "Observation/EjemploPatologiaDiagnostico" ]
     ], [
       fhir:index 1 ;
       fhir:link <https://emahealth.io/fhir/pathology/DiagnosticReport/EjemploPatologiaReport> ;
       fhir:Reference.reference [ fhir:value "DiagnosticReport/EjemploPatologiaReport" ]
     ]
  ] .

# - ontology header ------------------------------------------------------------

<https://emahealth.io/fhir/pathology/Composition/EjemploPatologiaComposition.ttl> a owl:Ontology ;
  owl:imports fhir:fhir.ttl .

# -------------------------------------------------------------------------------------